Class-12 Biology Ch-6 Molecular Basis of Inheritance MCQs Exam 2027 New

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📅 27/02/2026

Class-12 Biology Ch-6 Molecular Basis of Inheritance MCQs Exam 2027

Class-12 Biology Ch-6 Molecular Basis of Inheritance MCQs Exam 2027 Details: नीचे दिए गए सभी Questions Bihar Board परीक्षा 2027 के लिए “Very Very Important Multiple Choice Questions (MCQs) Objective” (अत्यंत महत्वपूर्ण प्रश्न) हैं। इन सभी Class 12th Biology /जीवविज्ञान ) = जीवविज्ञान भाग-1 (English Medium) Book Chapter-6 Molecular Basis of Inheritance का Questions का Solve का वीडियो Youtube और Website पर Upload किया है।

Class-12 Biology Ch-6 Molecular Basis of Inheritance MCQs Exam 2027

Biology Important MCQs (Topic-wise Syllabus: 175 Questions)

TOPIC 1: Structure of DNA and Chemical Composition

  1. DNA differs from RNA in having— [2020A]

    (A) Presence of Phosphate

    (B) Presence of Ribose

    (C) Presence of Deoxyribose

    (D) Presence of Cytosine

  2. Who provided the X-ray diffraction data of DNA? [2024A]

    (A) Maurice Wilkins and Rosalind Franklin

    (B) Chargaff

    (C) Watson and Crick

    (D) Holley

  3. Who proposed the Double Helix model of DNA? [2015A]

    (A) Morgan and Mendel

    (B) Watson and Crick

    (C) Khorana and Nirenberg

    (D) Griffith and Hershey

  4. ‘Uracil’ is specifically found in? [2012A]

    (A) DNA

    (B) RNA

    (C) Both

    (D) None

  5. Which bond is present between the nitrogenous bases of nucleic acids? [2022A]

    (A) Peptide bond

    (B) Ester bond

    (C) Glycosidic bond

    (D) Hydrogen bond

  6. DNA and RNA are similar in— [2023A]

    (A) Being capable of replication

    (B) Having similar sugar

    (C) Being polymers of nucleotides

    (D) Having similar pyrimidine bases

  7. Deoxyribose and Ribose sugars belong to the same class called— [2022A]

    (A) Trioses

    (B) Pentoses

    (C) Hexoses

    (D) Heptoses

  8. Which of the following DNA molecules contains Purine? [2021A]

    (A) A and C

    (B) C and T

    (C) A and G

    (D) None of these

  9. Nucleic acid is a strong acid. The reason for its acidity is—

    (A) Phosphate

    (B) Sugar

    (C) Nitrogen base

    (D) Hydrogen bond

  10. Which nitrogenous base is absent in DNA?

    (A) A

    (B) C

    (C) T

    (D) U

  11. In a DNA molecule, Cytosine always pairs with—

    (A) Thymine

    (B) Uracil

    (C) Guanine

    (D) Cytosine

  12. The pyrimidine bases present in DNA are—

    (A) Cytosine and Uracil

    (B) Adenine and Uracil

    (C) Cytosine and Thymine

    (D) Adenine and Thymine

  13. In the double helix model of DNA, what is the distance between each base pair?

    (A) 34 nm

    (B) 3.4 nm

    (C) 2 nm

    (D) 0.34 nm

  14. The basic unit of a nucleic acid molecule is called—

    (A) Nucleoside

    (B) Nucleotide

    (C) Nitrogenous base

    (D) Pentose sugar

  15. The number of hydrogen bonds between Cytosine and Guanine is—

    (A) 2

    (B) 3

    (C) 1

    (D) 4

  16. DNA differs from RNA by—

    (A) Nitrogenous bases and Sugars

    (B) Nitrogenous bases and Phosphate groups

    (C) Number of C atoms in sugars

    (D) Sugar and Phosphate groups

  17. Pyrimidines found in RNA are— [2021A]

    (A) Cytosine and Thymine

    (B) Adenine and Guanine

    (C) Cytosine and Uracil

    (D) Thymine and Uracil

  18. Nucleoside is— [2021A]

    (A) Sugar + Nitrogenous base

    (B) Sugar + Phosphate

    (C) Nitrogenous base + Phosphate

    (D) None of these

  19. If Cytosine is 18% in a DNA molecule, what will be the percentage of Adenine? [2021A]

    (A) 64%

    (B) 36%

    (C) 82%

    (D) 32%

  20. Which are the pyrimidine bases in DNA? [2016A]

    (A) Adenine and Guanine

    (B) Cytosine and Thymine

    (C) Adenine and Cytosine

    (D) Thymine and Guanine

TOPIC 2: DNA Packaging

  1. How many histone molecules are in the core of a nucleosome? [2020A]

    (A) 4

    (B) 6

    (C) 8 (Octamer)

    (D) 10

  2. Present in the nucleosome is—

    (A) Histone molecule

    (B) Nucleotide

    (C) Nucleoalbumin

    (D) Nuclear pore complex

  3. A typical nucleosome is composed of: [2026]

    (A) 200 base pairs of DNA

    (B) Histone octamer

    (C) Both (A) and (B)

    (D) Acidic protein

  4. What is present in the prokaryotic genetic system? [2014A]

    (A) Both DNA and Histone

    (B) DNA but no Histone

    (C) Histone but no DNA

    (D) Neither DNA nor Histone

  5. The arrangement of nucleotides in DNA can be seen by— [2022A]

    (A) Electron microscope

    (B) X-ray crystallography

    (C) Light microscope

    (D) Ultracentrifuge

  6. In a DNA helix, nucleotides are linked together by—

    (A) Glycosidic bond

    (B) Phosphodiester bond

    (C) Peptide bond

    (D) Hydrogen bond

  7. To which carbon of pentose sugar in a nucleoside is the nitrogen base attached?

    (A) 1

    (B) 2

    (C) 3

    (D) 5

  8. Which of the following is a nucleotide?

    (A) Uridylic acid

    (B) Cytosine

    (C) Thymidine

    (D) Glutamic acid

  9. DNA molecule is anti-parallel due to—

    (A) H-bond

    (B) Phosphodiester bond

    (C) Disulfide bond

    (D) None

  10. The number of nucleotides in one spiral of B-DNA is—

    (A) 5

    (B) 10

    (C) 21

    (D) 25

  11. If there are 10 spirals in DNA, the length of DNA will be—

    (A) 34 Å

    (B) 340 Å

    (C) 640 Å

    (D) 64 Å

  12. What is the diameter of a DNA molecule? [2026]

    (A) 10 Å

    (B) 20 Å

    (C) 34 Å

    (D) 2 Å

  13. The method used to test DNA is—

    (A) Iodine test

    (B) Feulgen reaction

    (C) Molisch test

    (D) Millon’s reagent

  14. The base pillar of both strands of DNA double helix is made of: [2026]

    (A) Sugar-Phosphate

    (B) Sugar-Nitrogenous base

    (C) Nitrogenous base – Phosphate

    (D) Sugar-Phosphate – Nitrogenous base

  15. In one helix of B-DNA spiral, there is— [2019A]

    (A) 2nm

    (B) 20 nm

    (C) 3.4 nm

    (D) 34 nm

TOPIC 3: DNA Replication

  1. Which organism was used by Meselson and Stahl to prove the semi-conservative nature of DNA replication? [2018A]

    (A) Drosophila

    (B) E. coli bacteria

    (C) Pea plant

    (D) Mouse

  2. On which strand of DNA are ‘Okazaki fragments’ formed? [2021A]

    (A) Leading strand

    (B) Lagging strand

    (C) Both

    (D) None of these

  3. When are Okazaki fragments formed? [2020A]

    (A) Continuous replication of DNA

    (B) Discontinuous replication of DNA

    (C) Lagging strand of DNA

    (D) Both (B) and (C)

  4. Which statement is false about DNA replication? [2024A]

    (A) The main enzyme of DNA replication is DNA polymerase

    (B) Any mistake in DNA replication results in mutation

    (C) Replication results in mutation due to errors

    (D) Replication is continuous on both strands of DNA

  5. DNA fragments are joined by—

    (A) Ligase

    (B) Polymerase

    (C) Helicase

    (D) Gyrase

  6. Who discovered DNA polymerase?

    (A) Okazaki

    (B) Kornberg

    (C) Meselson and Stahl

    (D) Watson and Crick

  7. In which phase of the cell cycle does DNA replication occur?

    (A) $G_1$

    (B) S

    (C) $G_2$

    (D) M

  8. Which enzyme is used to join Okazaki fragments? [2013A]

    (A) DNA polymerase

    (B) DNA ligase

    (C) Helicase

    (D) Nuclease

  9. During replication, the unwinding of DNA is done by which enzyme? [2021A]

    (A) Topoisomerase

    (B) Helicase

    (C) DNA polymerase

    (D) Primase

  10. In which direction does DNA replication take place? [2026]

    (A) 3′ to 5′

    (B) 5′ to 3′

    (C) In both directions

    (D) In any direction

  11. During replication, how is DNA synthesized on the ‘leading strand’? [2026]

    (A) Discontinuous

    (B) Continuous

    (C) In small fragments

    (D) In reverse direction

  12. What is the pitch of one helix of DNA? [2026]

    (A) 3.4 nm

    (B) 0.34 nm

    (C) 20 nm

    (D) 34 nm

  13. What was the conclusion of Hershey and Chase’s experiment? [2024A]

    (A) DNA is the genetic material of bacteria

    (B) DNA is the genetic material of viruses

    (C) RNA is the genetic material of bacteria

    (D) RNA is the genetic material of viruses

  14. Frederick Griffith discovered?

    (A) Translocation

    (B) Transformation

    (C) Transduction

    (D) Translation

  15. DNA is the genetic material of which of the following? [2021A]

    (A) TMV

    (B) Bacteriophage

    (C) Both (A) and (B)

    (D) None of these

  16. What did Hershey and Chase conclude based on their experiments? [2026]

    (A) Protein from virus enters bacteria

    (B) DNA from virus enters bacteria

    (C) RNA from virus enters bacteria

    (D) Transforming principle

  17. Which bacteria was used in Griffith’s experiment? [2026]

    (A) E. coli

    (B) Streptococcus pneumoniae

    (C) Bacillus subtilis

    (D) Salmonella

  18. When a separated piece of DNA is kept at 82°-92° C, then— [2022A]

    (A) There is no effect

    (B) It undergoes denaturation (unwinding)

    (C) It divides into a million pieces

    (D) It changes into RNA

  19. If the ratio of $(A+T)/(G+C)$ in one strand of a DNA molecule is 0.3, what will be the ratio of $(A+G)/(T+C)$ in the whole DNA?

    (A) 0.3

    (B) 0.6

    (C) 1.2

    (D) 1

  20. Which of the following is correct according to Chargaff’s rule?

    (A) $A + G = T + C$

    (B) $A = C$

    (C) $G = T$

    (D) $(A+T) / (G+C) = 1$

TOPIC 4: Transcription and RNA

  1. The synthesis of RNA on a DNA template is called— [2018A]

    (A) Translation

    (B) Transcription

    (C) Transduction

    (D) Replication

  2. The process of formation of RNA from DNA is called? [2011A/2023A]

    (A) Translation

    (B) Transcription

    (C) Translocation

    (D) Mutation

  3. Which form of RNA has a structure like a ‘Clover leaf’? [2023A]

    (A) mRNA

    (B) rRNA

    (C) hnRNA

    (D) tRNA

  4. Synthesis of RNA occurs on—

    (A) Both strands of DNA

    (B) Sense strand of DNA

    (C) Complementary strand of DNA

    (D) cDNA

  5. During transcription, RNA polymerase binds to which site on DNA?

    (A) Promoter

    (B) Regulator

    (C) Receptor

    (D) Acceptor

  6. Termination of transcription is done by? [2021A]

    (A) Cobalt gene

    (B) Rho-factor

    (C) Sigma factor

    (D) Catalyst

  7. What is another name for ‘Teminism’? [2026]

    (A) Transcription

    (B) Reverse Transcription

    (C) Translation

    (D) Replication

  8. Synthesis of DNA from RNA is defined as—

    (A) Central Dogma Reverse

    (B) Reverse Transcription

    (C) Teminism

    (D) All

  9. What is the process of removal of introns and joining of exons called? [2026]

    (A) Splicing

    (B) Tailing

    (C) Capping

    (D) Transcription

  10. In eukaryotes, which is involved in the transcription of t-RNA, 5S r-RNA, and Sn-RNA? [2018A]

    (A) RNA Polymerase I

    (B) RNA Polymerase II

    (C) RNA Polymerase III

    (D) All of these

  11. RNA Polymerase-III transcribes which of the following? [2026]

    (A) mRNA

    (B) rRNA

    (C) tRNA and 5S rRNA

    (D) hnRNA

  12. In which form of RNA is the ‘Anticodon’ found? [2026]

    (A) mRNA

    (B) rRNA

    (C) tRNA

    (D) hnRNA

  13. The most abundant RNA found in a cell is—

    (A) t-RNA

    (B) r-RNA

    (C) m-RNA

    (D) hn-r-RNA

  14. Which RNA is short-lived?

    (A) m-RNA

    (B) t-RNA

    (C) r-RNA

    (D) Sn-RNA

  15. Purines present in RNA are:

    (A) Guanine and Adenine

    (B) Uracil and Thymine

    (C) Adenine and Cytosine

    (D) Uracil and Guanine

  16. Which is correct for RNA?

    (A) [A] = [U]

    (B) [G] = [C]

    (C) [A] ≠ [U]

    (D) [A] = [G]

  17. Uracil is related to? [2019A]

    (A) RNA

    (B) DNA

    (C) Both (A) and (B)

    (D) None of these

  18. RNA is the genetic material of which of the following?

    (A) Prokaryotes

    (B) Eukaryotes

    (C) TMV

    (D) E. coli

  19. Which base is present in RNA but not in DNA?

    (A) Uracil

    (B) Guanine

    (C) Cytosine

    (D) Thymine

  20. What comes under ‘Central Dogma’? [2021A]

    (A) DNA → RNA → Protein

    (B) RNA → DNA → Protein

    (C) DNA → Protein → RNA

    (D) None of these

  21. What is the correct sequence of Central Dogma? [2026]

    (A) RNA → DNA → Protein

    (B) DNA → RNA → Protein

    (C) Protein → RNA → DNA

    (D) DNA → Protein → RNA

  22. Where does the process of ‘Transcription’ occur? [2026]

    (A) Cytoplasm

    (B) Nucleus

    (C) Ribosome

    (D) Mitochondria

  23. What will be the correct base sequence in DNA for the RNA base sequence ‘AUCGCUGA’? [2020A]

    (A) TTGCGGACT

    (B) TAGCGACT

    (C) UAGCGACU

    (D) TAGCCCACT

  24. If the sequence of bases in the coding strand of DNA is ATTCGATG, then the sequence of bases in mRNA will be—

    (A) TAAGCTAC

    (B) UAAGCUAC

    (C) ATTCGATG

    (D) AUUCGAUG

  25. Which form of RNA is also called ‘Soluble RNA’? [2016A]

    (A) mRNA

    (B) rRNA

    (C) tRNA

    (D) hnRNA

TOPIC 5: Genetic Code and Translation

  1. Which amino acid is coded by the start codon ‘AUG’? [2021A]

    (A) Valine

    (B) Methionine

    (C) Leucine

    (D) Alanine

  2. Which of the following is not a termination codon? [2024A]

    (A) UAG

    (B) UGA

    (C) AUG

    (D) UAA

  3. Some amino acids are coded by more than one codon. Such a code is called? [2024A]

    (A) Unambiguous

    (B) Degenerate

    (C) Universal

    (D) Specific

  4. What is the process of protein synthesis called? [2020A]

    (A) Transcription

    (B) Translation

    (C) Transduction

    (D) Transformation

  5. Who proposed the ‘Wobble hypothesis’? [2019A]

    (A) Crick

    (B) Watson

    (C) Nirenberg

    (D) Khorana

  6. Where is the genetic code located?

    (A) r-RNA

    (B) t-RNA

    (C) r-DNA

    (D) m-RNA

  7. Triplet UUU codes for?

    (A) Leucine

    (B) Methionine

    (C) Phenylalanine

    (D) Glycine

  8. If the codon in m-RNA is AAA, what will be its anti-codon?

    (A) UUU

    (B) AAA

    (C) TTT

    (D) AUG

  9. To which end of tRNA does the amino acid attach?

    (A) 5′ end

    (B) 3′ end

    (C) TψC loop

    (D) DHU loop

  10. Which of the following is a start codon? [2020A]

    (A) UAG and UGA

    (B) AUG and GUG

    (C) UAA and UAG

    (D) UAA and UGA

  11. The initiation codon for protein synthesis is?

    (A) AUG

    (B) GUA

    (C) GCA

    (D) CCA

  12. Which of the following genetic codes is a ‘Stop codon’? [2026]

    (A) AUG

    (B) UAA

    (C) GUG

    (D) UGG

  13. Who carries amino acids to the ribosome during protein synthesis? [2026]

    (A) mRNA

    (B) tRNA

    (C) rRNA

    (D) DNA

  14. Which of the following statements is incorrect about the genetic code? [2026]

    (A) The codon is triplet

    (B) It is unambiguous and specific

    (C) It is degenerate

    (D) All 64 codons code for amino acids

  15. What is meant by charging of tRNA? [2024A]

    (A) Attachment of amino acid to cognate tRNA

    (B) Attachment of tRNA to ribosome

    (C) Transcription of RNA

    (D) Transformation of RNA

  16. A polypeptide chain has 100 amino acids. How many types of proteins can be formed under triplet genetic code?

    (A) $20^{100}$

    (B) $100^{20}$

    (C) $100 \times 20 \times 3$

    (D) $100 \times 3$

  17. Out of 64 codons in the genetic code, how many codons code for 20 types of amino acids?

    (A) 61

    (B) 64

    (C) 20

    (D) 59

  18. What complementary bond exists between Codon and Anti-codon? [2019A]

    (A) Ionic bond

    (B) Covalent bond

    (C) Hydrogen bond

    (D) Phosphodiester bond

  19. Which of the following RNA is the smallest in protein synthesis? [2018A]

    (A) m-RNA

    (B) r-RNA

    (C) t-RNA

    (D) hn-RNA

  20. During translation, with whose help do amino acids read the code on mRNA? [2026]

    (A) rRNA

    (B) tRNA

    (C) DNA

    (D) Enzymes

  21. What are Transposons called?

    (A) Split gene

    (B) Mobile genetic element

    (C) Jumping gene

    (D) Both (B) and (C)

  22. Who discovered ‘Jumping Genes’ in maize? [2015A]

    (A) Hugo de Vries

    (B) T. H. Morgan

    (C) Barbara McClintock

    (D) Mendel

  23. In sickle cell anaemia, glutamic acid is replaced by which amino acid? [2017A]

    (A) Alanine

    (B) Valine

    (C) Leucine

    (D) Serine

  24. In gene mutation, Adenine is replaced by Guanine, this is—

    (A) Frame-shift mutation

    (B) Transversion

    (C) Transcription

    (D) Transition

  25. A DNA segment that reads the same forwards and backwards is called—

    (A) Palindromic DNA

    (B) Repetitive DNA

    (C) Plasmid DNA

    (D) Copy DNA

  26. Why was H.G. Khorana awarded the Nobel Prize?

    (A) For discovery of DNA

    (B) For discovery of RNA

    (C) For chemical synthesis of gene

    (D) For discovery of DNA polymerase

  27. Restriction endonucleases recognize a specific sequence in DNA— [2018A]

    (A) Palindromic nucleotide sequences

    (B) VNTR

    (C) Mini satellite

    (D) All of these

  28. GAATTC is the recognition site for which restriction endonuclease? [2018A]

    (A) Hind III

    (B) Eco RI

    (C) Bam I

    (D) Hae III

  29. Where does the process of Translation occur?

    (A) Nucleus

    (B) Cytoplasm

    (C) Mitochondria

    (D) Lysosome

  30. Where are anti-codons found? [2021A]

    (A) In mRNA

    (B) In tRNA

    (C) In rRNA

    (D) None of these

TOPIC 6: Gene Expression and Regulation (Lac Operon)

  1. What does the Operon model represent? [2021A]

    (A) Gene synthesis

    (B) Gene expression

    (C) Gene regulation

    (D) Gene function

  2. What is the role of ‘y’ gene in Lac Operon? [2024A]

    (A) Coding for Beta-galactosidase

    (B) Coding for Permease

    (C) Coding for Repressor gene

    (D) Coding for Transacetylase

  3. Control of gene expression occurs at which level? [2023A]

    (A) Transcription

    (B) Translation

    (C) DNA replication

    (D) Both (A) and (B)

  4. Lac Operon is a representative of? [2019A]

    (A) Inducible gene machinery

    (B) Repressible gene machinery

    (C) Housekeeping gene structure

    (D) All of these

  5. During expression of Operon, RNA polymerase binds to?

    (A) Structural gene

    (B) Operator gene

    (C) Regulator gene

    (D) Promoter gene

  6. Constantly active genes are—

    (A) Gene battery genes

    (B) Luxury genes

    (C) Housekeeping genes

    (D) Mild genes

  7. Who proposed the Operon model? [2021A]

    (A) Watson and Crick

    (B) Nirenberg

    (C) Jacob and Monod

    (D) None of these

  8. How many structural genes are found in Lac Operon? [2022A]

    (A) One (z)

    (B) Two (z, y)

    (C) Three (z, y, a)

    (D) Four (z, y, a, i)

  9. Who acts as ‘Inducer’ in Lac Operon? [2022A]

    (A) Glucose

    (B) Lactose

    (C) Galactose

    (D) Fructose

  10. Which enzyme causes lactose to enter the bacterial cell? [2026]

    (A) Beta galactosidase

    (B) Permease

    (C) Transacetylase

    (D) Lactase

  11. What is the ‘Regulator gene’ of the Operon model called? [2026]

    (A) Structural gene

    (B) Inhibitor (i) gene

    (C) Operator gene

    (D) Promoter gene

  12. In ‘Lac Operon’, the ‘z’ gene codes for? [2026]

    (A) Permease

    (B) Transacetylase

    (C) Beta-galactosidase

    (D) Repressor protein

  13. Regulation of gene expression occurs at which level?

    (A) Transcription

    (B) Processing/Splicing

    (C) Translation

    (D) All

  14. Expression of any gene is edited by which of the following? [2018A]

    (A) Small interfering RNA (RNAi)

    (B) Anti-sense RNA

    (C) Both A and B

    (D) None of these

  15. Which enzyme allows lactose to enter bacterial cells? [2026]

    (A) Beta galactosidase

    (B) Permease

    (C) Transacetylase

    (D) Lactase

  16. Which enzyme causes lactose to enter the bacterial cell? [2026]

    (A) Beta galactosidase

    (B) Permease

    (C) Transacetylase

    (D) Lactase

  17. ‘Housekeeping’ genes are those which:

    (A) Work occasionally

    (B) Are always active in the cell

    (C) Work only during division

    (D) Work on external stimulus

  18. Which model is most famous for gene regulation in prokaryotes?

    (A) Tatum model

    (B) Operon model

    (C) Crick model

    (D) Mendel model

  19. The Repressor protein binds to what to stop gene expression?

    (A) Promoter

    (B) Operator

    (C) Regulator

    (D) Structural gene

  20. The binding site of RNA polymerase is called:

    (A) Operator

    (B) Promoter

    (C) Intron

    (D) Codon

TOPIC 7: Human Genome Project and DNA Fingerprinting

  1. Who developed the technique of DNA Fingerprinting? [2017A]

    (A) Wilkins

    (B) Alec Jeffreys

    (C) Watson

    (D) Khorana

  2. When did the Human Genome Project (HGP) start? [2015A]

    (A) 1980

    (B) 1990

    (C) 2000

    (D) 1995

  3. What is the basis of DNA fingerprinting? [2022A]

    (A) Single nucleotide polymorphism

    (B) DNA polymorphism

    (C) Quantity of RNA

    (D) Quantity of protein

  4. Satellite DNA is a useful tool for— [2023A]

    (A) Sex determination

    (B) Organ culture

    (C) Forensic science

    (D) Tissue culture

  5. The human genome is composed of approximately how many base pairs?

    (A) $3 \times 10^9$ bp

    (B) $6 \times 10^9$ bp

    (C) 20000 – 30000 bp

    (D) $2.2 \times 10^4$ bp

  6. The total estimated number of genes in humans is—

    (A) 3000

    (B) 80,000

    (C) 30,000

    (D) $3 \times 10^9$

  7. Human chromosomes containing the highest and lowest number of genes respectively are?

    (A) Chromosome 21 and Y

    (B) Chromosome 1 and X

    (C) Chromosome 1 and Y

    (D) Chromosome X and Y

  8. What is the function of DNA fingerprinting? [2016A]

    (A) Identification of true parents of offspring

    (B) Identification of criminals in forensic labs

    (C) Obtaining information about suspected parents

    (D) All of these

  9. What is the full form of ‘VNTR’ in DNA fingerprinting? [2026]

    (A) Variable Number of Tandem Repeats

    (B) Various Number of Tandem Repeats

    (C) Variable Nucleotide Tandem Repeats

    (D) Variable Nucleotide Triple Repeats

  10. According to HGP, total nitrogen base pairs in a human cell are? [2026]

    (A) $3 \times 10^9$

    (B) $6 \times 10^9$

    (C) $2 \times 10^9$

    (D) $3 \times 10^6$

  11. In which field is DNA Fingerprinting used? [2026]

    (A) Forensic Science

    (B) Paternity testing

    (C) Checking genetic diversity

    (D) All of these

  12. How many sets of chromosomes are there in the human genome?

    (A) 23

    (B) 46

    (C) 22

    (D) 1

  13. Which radioactive substance is used as a probe in DNA Fingerprinting?

    (A) P-32

    (B) S-35

    (C) C-14

    (D) H-3

  14. Which is the largest known human gene?

    (A) Insulin gene

    (B) Dystrophin

    (C) Haemoglobin gene

    (D) Oncogene

  15. What was the Human Genome Project called?

    (A) Mini Project

    (B) Mega Project

    (C) Micro Project

    (D) Nano Project

TOPIC 8: Genetics, Evolution and Disorders

  1. How many chromosomes are in Turner’s syndrome? [2020A]

    (A) 45

    (B) 46

    (C) 47

    (D) None of these

  2. In which stage does crossing-over occur? [2021A]

    (A) Leptotene

    (B) Cytokinesis

    (C) Pachytene

    (D) Diakinesis

  3. If a person’s blood group is AB, what will be their genotype? [2026]

    (A) $I^AI^A$

    (B) $I^Bi$

    (C) $I^Ai$

    (D) $I^AI^B$

  4. If a plant’s genotype is AaBbCc, how many types of gametes will be formed? [2026]

    (A) Two

    (B) Four

    (C) Eight

    (D) Sixteen

  5. Which of these is not a chromosomal disorder? [2026]

    (A) Klinefelter’s syndrome

    (B) Turner’s syndrome

    (C) Down’s syndrome

    (D) Haemophilia

  6. In which animal does sex determination depend on the number of sets of chromosomes? [2026]

    (A) Birds

    (B) Honeybees

    (C) Grasshoppers

    (D) Mammals

  7. Which rule is based on monohybrid cross? [2026]

    (A) Law of dominance

    (B) Law of segregation

    (C) Law of independent assortment

    (D) Both (A) and (B)

  8. In which type of rocks are fossils found? [2026]

    (A) Sedimentary rock

    (B) Metamorphic rock

    (C) Igneous rock

    (D) All of these

  9. Which are examples of homologous organs in animals? [2026]

    (A) Eyes of octopus and human

    (B) Sweet potato and potato

    (C) Flippers of penguins and dolphins

    (D) Heart of reptiles and mammals

  10. Who among these was most like an ape? [2026]

    (A) Dryopithecus

    (B) Ramapithecus

    (C) Homo erectus

    (D) Australopithecus

  11. Which of these is the most resistant organic material? [2026]

    (A) Pectin

    (B) Cellulose

    (C) Sporopollenin

    (D) Chitin

  12. Which gases did Miller use in his experiment? [2026]

    (A) $CH_4, NH_3, H_2, H_2O$

    (B) $O_2, CO_2, N_2, H_2$

    (C) $CH_4, O_2, N_2$

    (D) None of these

  13. If a person’s blood group is AB, what would be his/her genotype? [2026]

    (A) $I^A I^A$

    (B) $I^B i$

    (C) $i i$

    (D) $I^A I^B$

  14. How many types of gametes would be formed if the genotype of plant is AaBbCc? [2026]

    (A) Two

    (B) Four

    (C) Eight

    (D) Sixteen

  15. Which of the following is not a chromosomal disorder? [2026]

    (A) Klinefelter’s syndrome

    (B) Turner’s syndrome

    (C) Down’s syndrome

    (D) Haemophilia

  16. In which animal does sex determination depend on the number of chromosome sets? [2026]

    (A) Birds

    (B) Honeybees

    (C) Grasshoppers

    (D) Mammals

  17. Which of the following laws is based on monohybrid cross? [2026]

    (A) Law of dominance

    (B) Law of segregation

    (C) Law of independent assortment

    (D) Both (A) and (B)

  18. Fossils are found in which type of rocks? [2026]

    (A) Sedimentary rock

    (B) Metamorphic rock

    (C) Igneous rock

    (D) All of these

  19. Which of the following are examples of homologous organs in animals? [2026]

    (A) Eyes of octopus and human

    (B) Sweet potato and potato

    (C) Flippers of penguins and dolphins

    (D) Heart of reptiles and mammals

  20. Which of the following was more like ape? [2026]

    (A) Dryopithecus

    (B) Ramapithecus

    (C) Homo erectus

    (D) Australopithecus

  21. Who discovered nuclear transplantation technique? [2023A]

    (A) Griffith

    (B) Gurdon

    (C) Briggs

    (D) Ian Wilmut

  22. What do analogous organs represent?

    (A) Convergent Evolution

    (B) Divergent Evolution

    (C) Parallel Evolution

    (D) None of these

  23. What was the atmosphere of Earth like at the time of origin of life?

    (A) Oxidizing

    (B) Reducing

    (C) Neutral

    (D) Very cold

  24. Darwin’s Finches are an example of?

    (A) Adaptive Radiation

    (B) Mutation

    (C) Isolation

    (D) Mutualism

  25. ‘Oparin-Haldane’ theory is related to?

    (A) Genetics

    (B) Chemical origin of life

    (C) Evolution

    (D) Ecology

  26. Who is the closest relative of humans?

    (A) Gorilla

    (B) Chimpanzee

    (C) Gibbon

    (D) Monkey

  27. Down’s Syndrome is caused by?

    (A) Trisomy of 21st chromosome

    (B) Trisomy of 18th chromosome

    (C) Deficiency of X chromosome

    (D) Excess of Y chromosome

  28. What kind of disease is Sickle Cell Anaemia?

    (A) Sex-linked

    (B) Autosomal recessive

    (C) Autosomal dominant

    (D) None of these

  29. What is the genetic makeup of Klinefelter’s Syndrome?

    (A) XO

    (B) XXY

    (C) XYY

    (D) XXX

  30. What is the exception to Mendel’s Law of Independent Assortment?

    (A) Linkage

    (B) Dominance

    (C) Segregation

    (D) Incomplete Dominance

Bihar Board Class 12th के (Biology/जीवविज्ञान ) = जीवविज्ञान ‘भाग-1 (Englsih Medium) Book Chapter- 6 Molecular Basis of Inheritance के Exam 2027 MCQs Questions Answer Key

Q.No.AnsQ.No.AnsQ.No.AnsQ.No.Ans
1(C)45(B)89(B)133(B)
2(A)46(B)90(B)134(C)
3(B)47(A)91(A)135(A)
4(B)48(B)92(B)136(C)
5(D)49(B)93(B)137(C)
6(C)50(B)94(D)138(D)
7(B)51(B)95(A)139(A)
8(C)52(B)96(A)140(A)
9(A)53(B)97(A)141(D)
10(D)54(D)98(C)142(D)
11(C)55(A)99(C)143(A)
12(C)56(B)100(B)144(B)
13(D)57(B)101(D)145(B)
14(B)58(D)102(C)146(A)
15(B)59(B)103(B)147(C)
16(A)60(A)104(D)148(D)
17(C)61(B)105(A)149(C)
18(A)62(B)106(C)150(D)
19(D)63(B)107(A)151(B)
20(B)64(A)108(B)152(D)
21(C)65(C)109(B)153(A)
22(A)66(C)110(B)154(D)
23(C)67(C)111(C)155(A)
24(B)68(B)112(B)156(C)
25(B)69(A)113(D)157(A)
26(B)70(A)114(A)158(D)
27(A)71(C)115(D)159(C)
28(A)72(A)116(C)160(D)
29(B)73(C)117(C)161(B)
30(B)74(A)118(C)162(D)
31(B)75(A)119(B)163(A)
32(B)76(B)120(B)164(D)
33(B)77(B)121(B)165(A)
34(A)78(B)122(C)166(B)
35(C)79(D)123(D)167(A)
36(B)80(C)124(C)168(B)
37(B)81(B)125(B)169(A)
38(D)82(C)126(B)170(B)
39(D)83(B)127(B)171(B)
40(A)84(B)128(B)172(A)
41(B)85(A)129(B)173(B)
42(B)86(D)130(B)174(B)
43(B)87(C)131(B)175(A)
44(B)88(A)132(B)

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